• Description
  • Additional information

Semaglutide Description

Important notice: Semaglutide is a prescription-only drug. It must only be used under physician supervision. Not for cosmetic weight loss without medical indication.

Basic Information

• Class: Long-acting GLP‑1 receptor agonist (glucagon-like peptide‑1 analog), developed by Novo Nordisk

• Molecular formula: \boldsymbol{C_{187}H_{291}N_{45}O_{59}}; Molecular weight: 4113.58 Da

• Structure modification: A C18 fatty di-acid side chain attached to lysine at position 26 for albumin binding, prolonging half-life; position 8 modified to resist DPP‑4 enzymatic degradation

• Brand names:

◦ Ozempic® (subcutaneous injection, type 2 diabetes)

◦ Wegovy® (subcutaneous injection, chronic weight management, 2.4 mg weekly dose)

◦ Rybelsus® (oral tablet, type 2 diabetes)

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